Table 1. Changes of blood biochemical characteristics by exposed to flutriafol in finishing pigs

Biochemical parameter Control T1 (×1) T2 (×5) T3 (×10) T4 (×50) T5 (×100) p-value
GLU (mg/dL) 87.40±2.89 89.89±3.19 85.07±3.30 83.08±2.30 82.19±2.86 85.81±3.75 0.5524
CREA (mg/dL) 0.95±0.03a 1.05±0.02a 0.97±0.05a 1.03±0.02a 0.91±0.03b 0.89±0.03b 0.0047
BUN (mg/dL) 9.67±0.44b 11.07±0.57a 8.13±0.70b 11.17±0.81a 12.38±0.58a 11.56±0.52a <0.0001
BUN/CREA 10.40±0.68b 10.60±0.64b 8.33±0.54b 11.00±0.94b 13.94±0.85a 13.06±0.47a <0.0001
PHOS (mg/dL) 7.31±0.23 7.23±0.27 7.18±0.23 7.15±0.23 7.36±0.20 7.56±0.20 0.8184
CA (mg/dL) 11.01±0.14 11.15±0.12 10.96±0.14 10.93±0.33 11.19±0.14 11.09±0.16 0.7952
TP (g/dL) 8.05±0.11a 7.95±0.06b 7.45±0.11b 7.61±0.25b 7.91±0.14b 8.48±0.15a <0.0001
ALB (g/dL) 3.87±0.11a 4.00±0.07a 3.57±0.08b 3.47±0.20b 3.73±0.10a 3.75±0.10a 0.0138
GLOB (g/dL) 4.19±0.11b 3.94±0.11b 3.88±0.09b 4.14±0.13b 4.18±0.09b 4.73±0.17a <0.0001
ALB/GLOB 0.93±0.05b 1.05±0.04a 0.93±0.03b 0.84±0.05b 0.91±0.03b 0.82±0.05b 0.0068
ALT (U/L) 45.93±2.18b 54.40±1.87b 49.13±1.65b 51.25±3.88b 44.88±2.75b 94.44±10.66a <0.0001
ALKP (U/L) 129.9±7.46 164.7±4.93 142.4±5.19 130.8±11.75 154.2±12.37 145.0±11.60 0.0898
GGT (U/L) 25.13±3.74b 14.93±1.32b 25.53±2.64b 22.58±1.58b 23.94±1.78b 29.13±4.36a 0.0242
TBIL (mg/dL) 0.32±0.13 0.21±0.02 0.19±0.02 0.26±0.02 0.35±0.11 0.39±0.07 0.4072
CHOL (mg/dL) 73.87±4.49 74.07±4.32 64.80±3.61 73.50±5.30 76.94±3.55 65.25±6.52 0.3195
AMYL (U/L) 539.7±30.28a 542.3±48.86a 523.9±26.11a 344.3±17.08b 521.8±62.43a 603.6±37.66a 0.0011
LIPA (U/L) 13.27±1.73b 16.07±2.11b 15.40±1.41b 12.00±0.91b 28.75±6.05a 20.88±2.76a 0.0038
Values are mean±SEM. n=20.
All traits in the table were analyzed by one-way ANOVA with Tukey's multiple comparison test.
Reference ranges: GLU (85–160), CREA (0.5–2.1), BUN (6–30), PHOS (3.6–9.2), CA (6.5–11.4), TP (6.0–8.0), ALB (1.8–3.3), GLOB (2.5–4.5), ALT (9–43), ALKP (92–294), GGT (16–30), TBIL (0.1–0.3), CHOL (18–79), AMYL (271–1,198), LIPA (10–44).
GLU, glucose; CREA, creatinine; BUN, blood urea nitrogen; PHOS, phosphate; CA, calcium; TP, total protein (TP=ALB+GLOB); ALB, albumin globulin; GLOB, globulin; ALT, alanine aminotransferase; ALKP, alkalinephosphatase; GGT, gamma glutamyl transpeptidase; TBIL, total bilirubin; CHOL, cholesterol; AMYL, amylase; LIPA, lipase.