| Identification of miRNA in bovine colostrum and mature milk and proposal of potential biomarkers for quality control of raw milk and dairy foods. | miR-26a, miR-26b, miR-200c, miR-21, miR-30d, miR-99a, and miR-148a could potentially be used as biomarkers for quality control in raw milk and dairy products | (Chen et al., 2010) |
| Identification and comparison of exosomal miRNA composition in human, caprine, and bovine colostrum and mature milk. | miR-30a-5p, miR-22-3p, and miR-26a are highly conserved in colostrum and mature milk of three mammals, including humans, caprine, and bovines. | (Yun et al., 2021) |
| Identification and comparing miRNAs in bovine colostrum and mature milk using microarray and qPCR analysis. | miR-15b, miR-27b, miR-34a, miR-106b, miR-130a, miR-155, and miR-223 are related to immunity or development and are more expressed in colostrum than mature milk. | (Izumi et al., 2012) |
| Identification of miRNA and mRNA of bovine milk exosomes and confirmation of uptake into human macrophages. | Among the analyzed miRNAs, 14 bovine-specific miRNAs (miR-2478, miR-2412, miR-2305, miR-2881, miR-2328*, miR-2888, miR-2304, miR-2391, miR-2892, miR-2887, miR-2316, miR-2374, miR-2291, and miR-2284l) were recognized. | (Izumi et al., 2015) |
| Comparison of miRNA distribution in milk EVs according to different ultracentrifugation. | The top 4 miRNAs of P12K and P35K were bta-let7a, bta-miR-30a, bta-miR-21, and bta-let7b, and bta-mir-10a and bta-mir-10b were most expressed in P70K and P100K, respectively. | (Benmoussa et al., 2020) |
| Identification and characterization of milk exosomal miRNAs in cows with mastitis. | Eighteen miRNAs, including four novel miRNAs (bta-let-7b, bta-miR-103, bta-miR-142-3p, bta-miR-142-5p, bta-miR-1468, bta-miR-146a, bta-miR-146b, bta-miR-147, bta-miR-221, bta-miR-223, bta-miR-2284w, bta-miR-2285b, bta-miR-23a, bta-miR-423-5p, etc.), had differential expression, and miR-223 and miR-142-5p were considered for use as potential biomarkers for the diagnosis of mastitis. | (Cai et al., 2018) |
| Profiling of expression of milk exosomal miRNA in cows infected with Staphylococcus aureus. | According to the presence or absence of infection, 14 miRNAs (bta-miR-142-5p, bta-miR-296-5p, bta-miR-223, bta-miR-1246, bta-miR-183, bta-miR-502b, bta-miR-378b, bta-miR-2285 g-3p, bta-miR-99a-5p, bta-miR-181b, bta-miR-101, bta-miR-10a, bta-miR-99b, and bta-miR-2419-5p) were expressed differently, in particular bta-miR-142-5p, and -223 were suggested as potential biomarkers for detection of infection. | (Sun et al., 2015) |
| Confirmation of changes in the expression of bovine milk EVs-miRNA as a result of changes in feed. | When fed on a nonforage fiber sources diet, 4 miRNAs (bta-miR-29c, bta-miR-760-3p, bta-miR-383, and bta-miR-11973) among milk EVs miRNAs were upregulated, and 5 miRNAs (bta -miR-328, bta-miR-10167-3p, bta-miR-103, bta-miR-885, and bta-miR-302d) were downregulated. | (Colitti et al., 2019) |