| Confirmation of cellular and intestinal uptake of milk exosomes loaded with curcumin, which is poorly absorbed. | (Komine-Aizawa et al., 2020) |
| By attaching hyaluronan, a CD44-specific ligand, to doxorubicin-loaded milk exosome, it enables specific transport of CD44 overexpressing cancer cells and induces tumor cell death. | (Li et al., 2020) |
| Development of a pH- and light-sensitive drug delivery system based on milk exosomes for highly active anticancer treatment of oral squamous carcinoma. | (Zhang et al., 2020) |
| Ultrasonically loaded bcl-2 siRNA into bovine milk exosomes crossed the cell membrane and inhibited tumor growth. | (Tao et al., 2020) |
| Development of efficient and nontoxic lactoferrin-poly-l-lysine mediated loading method for siRNA into bovine milk exosome | (Shandilya et al., 2020) |
| The therapeutic efficacy of Paclitaxel was significantly increased by loading Paclitaxel, an anticancer drug with low water solubility and strong toxicity, in bovine colostrum-derived exosomes. | (Kandimalla et al., 2021a) |
| Oral administration and confirmation of uptake of bovine milk EVs loaded with locked nucleic acid antisense oligonucleotides. | (Grossen et al., 2021) |
| Epicatechin gallate-loaded bovine milk exosomes have a neuroprotective role in rotenone-induced Parkinson’s disease. | (Luo et al., 2021) |
| Developed efficient oral delivery platform of siRNA by coating hydrophilic polyethylene glycol (PEG) on the surface of bovine milk exosomes and loading siRNA with cationic chemical transfection. | (Warren et al., 2021) |
| Evaluation of uptake in hepatic and intestinal cell lines of milk exosomes loaded with exogenous hsa-miR148a-3p. | (del Pozo-Acebo et al., 2021) |