Table 1. Gene enrichment analysis of DEGs in mouse small intestine that PBS versus mRANKL_CE

	Category	GO ID	GO term	Bg_Gene	Tg_Gene	Bg_Gene	Tg_Gene	p-value	Odds ratio
Up-regulated	Biological_process	GO:0006458	‘De novo’ protein folding	17,865	49	37	4	6.32E-06	39.35
	Biological_process	GO:0006986	Response to unfolded protein	17,865	49	71	5	3.17E-06	25.66
	Biological_process	GO:0045124	Regulation of bone resorption	17,865	49	50	2	0.010	14.57
	Biological_process	GO:0070564	Positive regulation of vitamin D receptor signaling pathway	17,865	49	3	1	0.011	120.77
	Molecular_function	GO:0031072	Heat shock protein binding	17,865	49	146	6	6.63E-06	14.98
	Molecular_function	GO:0005509	Calcium ion binding	17,865	49	597	5	0.031	3.05

DEGs, differentially expressed genes; PBS, phosphate-buffered saline; mRANKL_CE, recombinant Lactococcus lactis expressing mouse receptor activator of NF-kB ligand; GO, gene ontology.