Table 2. Gene enrichment analysis of DEGs in mouse small intestine that WT_CE versus mRANKL_CE

	Category	GO ID	GO term	Bg_Gene	Tg_Gene	Bg_Gene	Tg_Gene	p-value	Odds ratio
Up-regulated	Molecular_function	GO:0005509	Calcium ion binding	17,865	159	597	20	2.10E-06	3.76
	Molecular_function	GO:0005516	Calmodulin binding	17,865	159	188	11	2.72E-06	6.57
	Biological_process	GO:0006458	‘De novo’ protein folding	17,865	159	37	2	0.047	6.07

DEGs, differentially expressed genes; WT_CE, wild-type Lactococcus lactis IL1403; mRANKL_CE, recombinant L. lactis expressing mouse receptor activator of NF-kB ligand; GO, gene ontology.