Table 4. Baseline characteristics of the animal experiments on weight and other obesity-related indicators in the blood of diet-induced obesity mice receiving a high-fat diet
Parameters | Groups |
ND | HFD | Xen | LGG | 299v | KC3 |
Bodyweight (g) |
Final | 29.3±2.51*** | 41.4±2.32 | 30.5±1.56*** | 36.0±2.11*** | 39.0±3.12 | 34.4±2.81*** |
Weight gain | 11.5±1.87*** | 22.5±1.98 | 11.7±1.05*** | 18.9±1.60*** | 21.4±2.46 | 16.7±2.36*** |
Organ weight (g) |
Liver | 1.04±0.29*** | 1.528±0.13 | 1.26±0.13*** | 1.22±0.05*** | 1.44±0.27 | 1.20±0.09*** |
EAT | 0.81±0.14*** | 2.026±0.17 | 0.75±0.260*** | 1.73±0.39 | 1.81±0.28 | 1.64±0.37* |
MAT | 0.34±0.07*** | 0.893±0.27 | 0.246±0.10*** | 0.57±0.18* | 0.76±0.29 | 0.52±0.14*** |
SAT | 0.38±0.08*** | 1.247±0.39 | 0.363±0.16*** | 0.97±0.33 | 1.12±0.20 | 0.91±0.28* |
Serum (mg/dL) |
Total cholesterol | 102.9±8.55*** | 164.4±25.3 | 92.0±20.1*** | 126.7±26.0** | 133.3±49.0 | 90.7±18.0*** |
TG | 106.3±24.3 | 109.3±12.0 | 74.0±9.32*** | 97.3±29.2 | 100.0±14.1 | 76.0±13.2*** |
LDLC | 9.14±3.02*** | 24.9±7.42 | 10.0±3.70*** | 16.0±5.06* | 18.7±10.9 | 10.7±4.13*** |
The whole bodyweight, liver and adipose tissues were measured after 12 weeks from the initial point (n=6–9). The indicators for the serum analysis were measured by the blood analyzer. The data are represented as the mean±SD and analyzed in a comparison with the HFD group.
p<0.05,
p<0.01,
p<0.001 by Fisher’s LSD test.
ND, control group with a normal chow diet; HFD, positive control group with a high-fat diet; Xen, negative control group treated with Xenical; LGG, receiving Lactobacillus rhamnosus strain GG mixed with a high-fat diet; 299v, receiving Lactiplantibacillus plantarum strain 299v mixed with a high-fat diet; KC3, receiving L. plantarum strain KC3 mixed with a high-fat diet; EAT, epidydimal adipose tissue; MAT, mesenteric adipose tissue; SAT, subcutaneous adipose tissue; TG, triacyl-glyceride; LDLC, low density lipoprotein cholesterol.