Table 1. Constituents and concentrations of synthetic digestive juices used in the human in vitro digestion model

Variable	Saliva (oral digestion step)	Gastric juice (gastrointestinal digestion step)	Duodenal juice (small intestinal gisgetion step)	Bile juice (small intestinal gisgetion step)
Inorganic and organic components	1.7 mL NaCl (175.3 g/L)8 mL urea (25 g/L)15 mg uric acid	6.5 mL HCl (37 g/L)18 mL CaCl2 2H2O(22.2 g/L)1 g bovine serum albumin	6.3 mL KCl (89.6 g/L)9 mL CaCl2 2H2O(22.2 g/L)1 g bovine serum albumin	69.3 mL NaHCO3 (84.7 g/L)10 mL CaCl2 2H2O(22.2 g/L)1.8 g bovine serum albumin 30 g bile
Enzymes	290 mg α-amylase25 mg mucin	2.5 g pepsin3 g mucin	9 g pancreatin1.5 g lipase	-
pH	6.8±0.2	1.50±0.02	8.0±0.2	7.0±0.2