Table 1. Cases of producing cultured meat using various growth factors and various cell types

Growth factors Cells Topics References
rAlbumin Small satellite cells Establishing an effective protocol for establishing bovine satellite cells by adding recombinant albumin instead of serum Stout et al. (2022)
Insulin-like growth factor, fibroblast growth factor, transforming growth factors, platelet-derived growth factor Fish embryonic stem cells Development of serum-free media reduces global warming potential, production costs, and optimizes cell growth rates Nikkhah et al. (2023)
Chlorella vulgaris extract Bovine myoblasts Establish a sustainable culture system free of animal serum and grain-derived nutrients Yamanaka et al. (2023)
C. vulgaris extract Bovine myoblasts Identifying the potential of C. vulgaris to establish an environmentally friendly cultured meat production process Okamoto et al. (2022)
Fermented soybean meal, edible insect hydrolysate Porcine muscle stem cells Determine proliferation and differentiation capacity and potential as a fetal human serum substitute Kim et al. (2023a)
Rapeseed protein isolate Small satellite cells Produce media with rapeseed protein isolate to replace albumin, serum to reduce media costs Stout et al. (2023)
Insect hydrolysate, marine invertebrate, hydrolysates Fish embryonic stem cells Evaluating the potential of black soldier flies, crickets, oysters, mussels, and midges as serum substitutes for aquaculture fish production Batish et al. (2022)
C-Phycocyanin C2C12 Evaluate the efficiency of mass production with C-phycocyanin to optimize production processes and costs Park et al. (2021b)
Egg whites, eggshell membrane, poultry residue, pea hydrolysate, porcine plasma, fibroblast growth factor Mammalian cells Environmental impact assessment of fetal bovine serum media versus serum replacement media Wali et al. (2024)
Fibroblast growth factor 2 Small satellite cells Identify signaling pathways that promote cell proliferation to develop serum-free media that stimulate satellite cell growth Yu et al. (2023)
Egg white extract Chick satellite cells Develop an efficient egg white extract preparation protocol to replace fetal human serum Lee et al. (2024b)
Lupin, peas, rapeseed, birds, yeast Fish satellite cells Validated the feasibility of supporting mackerel satellite cell growth in media with reduced production costs using agricultural waste and low-cost raw materials Lim et al. (2024)
Chlorococcum littorale C2C12 Develop a sustainable circulating cell culture system that nourishes cells and allows waste media to be recycled Haraguchi et al. (2022)
Auxenochlorella pyrenoidosa Fish muscle cells Evaluating the potential of A. pyrenoidosa to promote cell proliferation and mass production in goldfish Dong et al. (2023)
Fermented Okara C2C12 Pig immortalized myoblasts Identifying Okara’s potential as a serum substitute Teng et al. (2023)
Anabaena sp. PCC 7120 C2C12 QM7 Evaluation of the potential of Anabaena sp. PCC 7120 extract as an inhibitor of cell proliferation and growth in medium supplemented with algae extract Ghosh et al. (2023)